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The Patty Duke Show is an American sitcom that ran on ABC from September 18, 1963, to April 27, 1966, with reruns airing through August 31. The show was created as a vehicle for rising star Patty Duke. One hundred and five episodes were produced, 104 of them airing over three seasons, most written by either Sidney Sheldon or William Asher, who co-created the series.